Molecular Biology

Proprietary Biotech Platform

How Genviro transforms natural essential oils into high-potency pest control solutions by targeting neural pathways exclusive to insects.

Platform Overview

Bridging the Potency Gap

It has been known for centuries that plant essential oils protect host plants through killing and/or repelling insects and fungus. Historically, however, the lower potency of plant essential oils, when compared to synthetic chemical pesticides, has severely limited their commercial use.

GENVIRO has solved this problem. We developed a proprietary platform which allows us to increase the potency and effectiveness of naturally-occurring plant essential oil products.

Using this platform technology, we created unique synergistic blends of plant-derived essential oils which perfectly target specific receptors signaling cascades in the insects our products are designed to protect against. When these receptors are targeted, the insects are killed and/or repelled.

Our founder, Dr. Essam Enan, was the first in the world in 1996 to discover that octopamine receptors and tyramine receptors are the primary targets for plant essential oils in insects. Learn more about our founder.

Plant Chemistry

What Exactly Are Essential Oils?

You may be familiar with essential oils from many different industries, from fragrances and cosmetics to flavoring and spices, to pharmaceuticals that treat diseases. But biochemically, what are they?

Plant essential oils are a byproduct of a natural process called glucose oxidation that occurs during plant photosynthesis. Essential oils are then stored in all parts of a plant like leaves, seeds, stems, and roots.

The quality of essential oils differs greatly based on the region of the world where they grow and are cultivated, the weather, the type of soil, the time of harvesting, and the extraction method. That’s why GENVIRO makes every effort to source high-quality essential oils to deliver safe and highly effective products.

Evolutionary Biology

Preventing Insect Resistance

How well traditional insecticides work declines over time because insects develop resistance. Genviro's multi-target chemistry breaks this evolutionary loop.

How It Works

Resistance happens when mutations occur in the insect or organism to help them survive, much like how viruses mutate to survive. Traditional pesticides target a single receptor, making it easy for a single mutation to render the chemical useless.

Traditional Pesticides

Target only one specific receptor protein.
A single random mutation in the insect creates complete resistance.
Efficacy declines rapidly within a few years of commercial application.
Forces farmers and households to use stronger, more toxic chemicals.

The Genviro Solution

Synergistic blends target multiple different receptor proteins simultaneously.
Insects would need multiple mutations at the exact same time to survive.
Statistically improbable for multiple specific mutations to occur concurrently.
Formulations stay highly effective for a long time.

Safety Approvals & Standards

Our products strictly use ingredients that meet the highest standards of safety set by United States regulatory agencies.

EPA 25b Exempt

Ingredients on the U.S. Environmental Protection Agency's lowest-hazard exempt list.

FDA GRAS List

U.S. Food & Drug Administration's "Generally Recognized As Safe" ingredients.

FDA OTC List

Compliant with regulatory standards for Over The Counter safety formulations.

Literature

Relevant Published Research

Review the peer-reviewed research papers verifying the target site action of essential oils, co-authored by our founder.

Published Papers & Studies

1
Lei, J, Leser, MJ, Enan, EE. 2010. Nematicidal activity of two monoterpenoids and SER-2 tyramine receptor of Caenorhabditis elegans. Biochem Pharmacol, 79: 1062 – 1071.
2
Essam Enan. 2005. Molecular and pharmacological analysis of an octopamine receptor from American cockroach and fruit fly in response to plant essential oils. Arch. Insect Biochem. Physiol. 59: 161-171.
3
Essam Enan. 2005. Molecular response of Drosophila melanogaster tyramine receptor cascade to plant essential oils. Insect Biochem. Mol. Biol. 35: 309-321.
4
Larry J. Bischof and Essam Enan. 2004. Cloning, expression and functional analysis of an octopamine receptor from Periplaneta Americana. Insect Biochem. Mol. Biol. 34: 511-521.
5
Essam Enan. 2001. Insecticidal activity of essential oils: octopaminergic sites of action. Comp. Biochem. Physiol. Part C 130 (3): 325-337.
6
Nadia E. Abou El Ele, Essam Enan. 2001. Insecticidal activity of some essential oils: cAMP mediates effect. Bulletin of High Institute of Public Health, University of Alexandria, Alexandria, Egypt. 31 No 1, 15-30.